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suggest that the improvement in insulin parameters could be due to the inhibition of COX-2 expression, P-selectin, or inflammatory cytokines such as TNF- and IL-1

Exploratory Research in Clinical and Social Pharmacy

Many studies suggested a relationship between acetylation phenotypes (in particular, arising from NAT2 genotypes) and the risk of various cancer including colorectal, liver, breast, prostate, head and neck (Agndez, 2008) and other disease conditions such as birth defects (Lammer et al., 2004) or neurodegenerative and autoimmune diseases (Ladero, 2008)